C4859-1ML Display Image

Cycloheximide solution, Ready-Made Solution, microbial, 100 mg/mL in DMSO, 0.2 mum filtered

Code: C4859-1ML D2-231

Biochem/physiol Actions

Cycloheximide (CHX) is an antibiotic produced by S. griseus. Its main biological activity is translation inhibition in eukaryotes resulting i...


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Your Price
£143.00 1ML

Biochem/physiol Actions

Cycloheximide (CHX) is an antibiotic produced by S. griseus. Its main biological activity is translation inhibition in eukaryotes resulting in cell growth arrest and cell death. CHX is widely used for selection of CHX-resistant strains of yeast and fungi, controlled inhibition of protein synthesis for detection of short-lived proteins and super-induction of protein expression, and apoptosis induction or facilitation of apoptosis induction by death receptors.

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.Hygroscopic. Storage class (TRGS 510): Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials.

Packaging

1 mL in glass bottle

Specificity

Tested for cell growth arrest, selection of cycloheximide resistant yeast, apoptosis induction, and facilitation of apoptosis induction by FasL.

antibiotic activity spectrumfungi, yeast
biological sourcemicrobial
concentration100 mg/mL in DMSO
descriptionsuitable for testing specifications (CHO C. growth inhibitor)
formsolution
Gene Informationhuman ... FKBP1A(2280), PIN1(5300)
InChI keyYPHMISFOHDHNIV-FSZOTQKASA-N
InChI1S/C15H23NO4/c1-8-3-9(2)15(20)11(4-8)12(17)5-10-6-13(18)16-14(19)7-10/h8-12,17H,3-7H2,1-2H3,(H,16,18,19)/t8-,9-,11-,12+/m0/s1
mode of actionprotein synthesis | interferes
Quality Level300
SMILES stringO=C1[C@@]([C@H](O)CC2CC(NC(C2)=O)=O)([H])C[C@@H](C)C[C@@H]1C
solubilityDMSO: soluble
storage temp.2-8°C
Cas Number66-81-9
Hazard Class6.1
Un Number2810
Pack GroupII
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