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Neuraminidase from Vibrio cholerae, Type II, buffered aqueous solution, 8-24 units/mg protein (Lowry, using NAN-lactose)

Code: N6514-1UN D2-231

Application

Neuraminidase from Vibrio cholera has been used in a study to describe a five-step purification method. It has also been used in a study to investigate ...


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£141.00 EACH

Application

Neuraminidase from Vibrio cholera has been used in a study to describe a five-step purification method. It has also been used in a study to investigate modification of leukemia L1210 tumor cells.

Neurminidase is used as a cell-surface probe for glycoconjugate distribution and in substrate specificity studies.

General description

Calorimetry studies show that the two lectin-like domains flanking the central catalytic domain of Neuraminidase serve as the recognition and binding sites for sialic acid-containing substrates.

Neuraminidase enzymes are hydrolase enzymes that promote influenza virus release from infected cells and facilitate virus spread.

Physical form

Solution in 50 mM sodium acetate, pH 5.5, containing 0.15 M sodium chloride and 4 mM calcium chloride, 0.2 µm filtered..

Preparation Note

A further purification by affinity chromatography of our Type III.

Quality

Preservative free.

Unit Definition

One unit will liberate 1.0 µmole of N-acetylneuraminic acid per min at pH 5.0 at 37 °C using NAN-lactose or bovine submaxillary mucin, unless otherwise specified. Prices based on units using NAN-lactose as substrate.

biological sourceVibrio cholerae
foreign activityProtease and NAN-aldolase, present
formbuffered aqueous solution
Quality Level200
specific activity8-24 units/mg protein (Lowry, using NAN-lactose)
storage temp.2-8°C
typeType II
Cas Number9001-67-6
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